Unfortunately, the info on the use of high dose anabolic steroids in humans are mainly provided as case stories or small studies that lack sufficient management teams. In addition, the info available in the literature doesn’t account for the steroid type or dose, as neither could additionally be known. Patients additionally could additionally be taking concomitant stimulants, such as ephedra, which might confound data and the potential for adverse occasions. It is most likely going that the frequency of cardiac occasions is underreported within the medical literature. Supraphysiologic doses of anabolic-androgenic steroids , which include more than 30 natural and synthetic derivatives of testosterone, may trigger a large spectrum of clinical sequalae.
- Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996).
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We report a case of an acute ST-segment elevation myocardial infarction in a affected person with traditional cardiac threat factors using supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this patient additionally had polycythemia, doubtless secondary to high-dose testosterone. The affected person underwent successful percutaneous intervention of the right coronary artery. Physicians and sufferers should be conscious of the clinical consequences of anabolic steroid abuse.
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